Lysozyme is an inducible marker of macrophage activation in murine tissues as demonstrated by in situ hybridization.

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Lysozyme is an inducible marker of macrophage activation in murine tissues as demonstrated by in situ hybridization

This study demonstrates the induction of lysozyme mRNA expression in situ in tissue macrophages (M phi) of mice following in vivo stimulation. The resting resident tissue M phi of most tissues do not contain enough lysozyme mRNA to be detected by in situ hybridization using 35S-labeled RNA probes. Following Bacille Calmette Guerin or Plasmodium yoelli infection, however, M phi recruited to live...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1991

ISSN: 0022-1007,1540-9538

DOI: 10.1084/jem.174.5.1049